Ministry | Honourable Commissioner |
| Ministry of Agriculture | – |
| Ministry of Budget & Planning | Mr. Kingsley Anosike |
| Ministry of Tertiary Education | Prof. Eme Uche Eme |
| Ministry of Environment | Mr. Philemon A Ogbonna |
| Ministry of Finance | Mr. Uwaoma Ukandu |
| Ministry of Health | Prof. Enoch Ogbonnaya Uche |
| Ministry of Information | Mr. Okey Kanu |
| Ministry of Justice/Attorney-General | Mr. Ikechukwu Uwanna |
| Ministry of Lands & Housing | Mr. Chaka Chukwumerije |
| Ministry of Local Government /Chieftaincy Affairs | Prince Uzo Nwachukwu |
| Ministry of Petroleum & Mineral Resources | Prof. Joel F Ogbonna |
| Ministry of Science & Technology | Mr. David Kalu |
| Ministry of Sports & Youth Development | Mr. Nwaobilor Ananaba |
| Ministry of Trade & Commerce | Mr. Kingsley Chibueze Nwokocha |
| Ministry of Women Affairs | Dr. Mrs. Maureen Ijeoma Aghukwa |
| Ministry of Works | Engr. Don Otumchere Oti |
| Ministry of Transport | Dr. Chimezie Ukaegbu |
| Ministry of Power & Public Utilities | Eng. Ikechukwu Monday |
| Ministry of Industry & SMEs | Mr. Mike Akpara |
| Hon. Commissioner for Poverty Alleviation and Social Protection | Mrs. Blessing Ngozi Felix |
| Hon. Commissioner for Basic and Secondary Education | Mr. Goodluck Ubochi |
| Hon. Commissioner for Arts, Culture & Creative Economy | Mr. Mathew Ekwuruibe |
| Hon. Commissioner for Labour & Productivity | Comrade Sunny A. Onwuma |
